Search Results - PHARMACOLOGY OF DRUGS AFFECTING THE CARDIOVASCULAR SYSTEM
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Drug Repositioning Applied to Cardiovascular Disease in Mucopolysaccharidosis
Published in Life (2022-12-01)Get full text
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Role of Arginase 2 as a potential pharmacological target for the creation of new drugs to correct cardiovascular diseases
Published in Research Results in Pharmacology (2020-03-01)“…The modern possibilities of treatment of endothelial dysfunction in the pathology of the cardiovascular system and the possibility of creation of new drugs are considered. …”
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Pharmacogenetics of cardiovascular drugs
Published in Medicinski Podmladak (2023-01-01)“…Individual variations in the patient's response to the administered drugs are a frequent and important clinical problem in medicine and pharmacology. …”
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A quantitative systems pharmacology approach to predict the safe‐equivalent dose of doxorubicin in patients with cardiovascular comorbidity
Published in CPT: Pharmacometrics & Systems Pharmacology (2021-12-01)“…In this study, a translational quantitative system pharmacology‐pharmacokinetic‐pharmacodynamic (QSP‐PK‐PD) model was developed based on preclinical study to predict the safe‐equivalence dose of doxorubicin in patients with or without cardiovascular disease. …”
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Redefining space pharmacology: bridging knowledge gaps in drug efficacy and safety for deep space missions
Published in Frontiers in Space Technologies (2024-10-01)“…These alterations can potentially influence drug pharmacokinetics and pharmacodynamics, affecting the efficacy and safety of medications administered to astronauts. …”
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Metabolic Modulators in Cardiovascular Complications of Systemic Lupus Erythematosus
Published in Biomedicines (2023-11-01)Get full text
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Modulation of Reactive Oxygen Species Homeostasis as a Pleiotropic Effect of Commonly Used Drugs
Published in Frontiers in Aging (2022-06-01)“…Consequently, modulation of ROS homeostasis by nutrition, exercise, or pharmacological interventions is critical in aging. Numerous nutrients and approved drugs exhibit pleiotropic effects on ROS homeostasis. …”
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Evaluation of therapeutic strategies targeting BCAA catabolism using a systems pharmacology model
Published in Frontiers in Pharmacology (2022-11-01)Get full text
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POTENTIAL NEGATIVE EFFECTS OF OSTEOARTHRITIS ON THE CARDIOVASCULAR SYSTEM AND THE ROLE OF REHABILITATION IN THEIR REDUCTION
Published in Trakia Journal of Sciences (2025-10-01)“…Another mechanism affecting the cardiovascular system is the use of medication to control osteoarthritis symptoms. …”
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Antiosteoporosis Effects, Pharmacokinetics, and Drug Delivery Systems of Icaritin: Advances and Prospects
Published in Pharmaceuticals (2022-03-01)“…Osteoporosis is a systemic skeletal disorder affecting over 200 million people worldwide and contributes dramatically to global healthcare costs. …”
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