Search Results - PHARMACOLOGY OF DRUGS AFFECTING THE ENDOCRINE
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The classic azole antifungal drugs affect steroidogenic activity in a human term placenta model
Published in Pharmacological Research (2025-10-01)Get full text
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Comparative Pharmacological and Pharmaceutical Perspectives on Antidiabetic Therapies in Humans, Dogs, and Cats
Published in Pharmaceutics (2025-08-01)“…<b>Background/Objectives:</b> Diabetes mellitus (DM) is an increasingly prevalent endocrine disorder affecting humans and companion animals. …”
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Metabolic and Endocrine Insights in Donkeys
Published in Animals (2024-02-01)“…Equine treatment protocols apply to donkeys, although pharmacological studies for most drugs, except pergolide, are lacking.…”
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Side Effects of Human Drug Use: An Overview of the Consequences of Eels’ Exposure to Cocaine
Published in Fishes (2023-03-01)Get full text
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A review of the effects of pharmaceutical pollutants on humans and aquatic ecosystem
Published in Exploration of Drug Science (2024-08-01)“…This research aimed to examine studies investigating the occurrence of antibiotics, endocrine disruptors, and other pharmaceutical products in water, sediments, and organisms within aquatic ecosystems. …”
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Pharmacological properties and therapeutic potential of berberine: a comprehensive review
Published in Frontiers in Pharmacology (2025-08-01)“…In recent decades, the pharmacological properties of botanical drugs have been investigated with increasing depth, offering novel insights into their potential for enhancing healthcare. …”
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Pharmacological methods for weight reduction and their connection with the human gut microbiota
Published in Pharmacia (2023-12-01)“…During the last decade, significant advancements have been made in regard to treatment of many endocrine and metabolic conditions, using pharmacological means, and some of these novel medications have proven to be an effective therapy for obesity. …”
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Animal experiments and network pharmacology to explore the anti-inflammatory mechanism of dapagliflozin in the treatment of polycystic ovary syndrome
Published in Gynecological Endocrinology (2025-12-01)“…Pathological changes in the ovaries were examined by H&E staining, changes in ovarian tissue cell apoptosis were identified using TdT-mediated dUTP Nick-End Labeling (TUNEL) staining, and changes in inflammation-related factors were detected using immunohistochemistry and Western blotting analysis. Network pharmacology was used to predict the inflammatory targets and pathways affected by dapagliflozin in treating PCOS, and the potential interactions between dapagliflozin and inflammation-related target proteins were evaluated through molecular docking.Results Our results demonstrated that dapagliflozin treatment significantly improved PCOS symptoms, recovered ovarian morphology and physiological functions, and reduced the apoptosis of ovarian cells after drug intervention. …”
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Integrated bioinformatics and network pharmacology to explore the therapeutic target and molecular mechanisms of Bailing capsule on polycystic ovary syndrome
Published in BMC Complementary Medicine and Therapies (2023-12-01)“…This study demonstrated that BL exerted anti-PCOS effects via PIK3CA, ESR1, AKT, PPARG, and IRS1 targets affecting PI3K-Akt signaling pathways. Discussion This research clarified the multicomponent, multitarget, and multichannel action of BL and provided a theoretical reference for further investigations on its pharmacological basis and molecular mechanisms against PCOS.…”
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Hypertension in Thyroid Disorders
Published in Frontiers in Endocrinology (2019-07-01)Get full text
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Anti-hypertensive drugs deprescribing: an updated systematic review of clinical trials
Published in BMC Family Practice (2021-10-01)Get full text
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Female Gender as a Risk Factor for the Development of Drug-Induced Diseases
Published in Безопасность и риск фармакотерапии (2021-07-01)“…The aim of the study was to analyse and systematise data on the factors responsible for increased risk of drug-induced diseases in women. It was demonstrated that the increased risk of complications in women following the use of certain pharmacological classes of drugs is associated with a combination of factors that affect pharmacokinetics and pharmacodynamics. …”
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The Role of Pharmacists in Identifying and Preventing Drug-Related Problems in PCOS Management
Published in Pharmacy (2025-07-01)“…Polycystic ovary syndrome (PCOS) is an endocrine disorder prevalent in women of reproductive age, often requiring complex pharmacological management. …”
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The interplay between microbiota and brain-gut axis in epilepsy treatment
Published in Frontiers in Pharmacology (2024-01-01)Get full text
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A retrospective observational study on case reports of adverse drug reactions (ADRs) to tirzepatide
Published in Frontiers in Pharmacology (2025-07-01)Get full text
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