Search Results - BIOPROCESS ENGINEERING LAB

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    Implementation and use of cloud-based electronic lab notebook in a bioprocess engineering teaching laboratory by Erin M. Riley, Holly Z. Hattaway, P. Arthur Felse

    Published in Journal of Biological Engineering (2017-11-01)
    “…Results Implementation of ELN in the bioprocess engineering lab course, an analysis of user experiences, and our development actions to improve ELN training are presented here. …”
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    Enhancement of lignocellulosic degradation in high-moisture alfalfa via anaerobic bioprocess of engineered Lactococcus lactis with the function of secreting cellulase by Qinhua Liu, Junfeng Li, Jie Zhao, Jingxing Wu, Tao Shao

    Published in Biotechnology for Biofuels (2019-04-01)
    “…Currently, there have been negative effects on the combination of cellulases and lactic acid bacteria (LAB) on processing high-moisture alfalfa silage; however, transgenically engineered LAB strains that secrete cellulase have been proposed as an alternative approach to avoid the above problem. …”
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    Low code, high impact: Application of low-code platforms to enable and democratize the development of laboratory digitalization and automation applications by Jonas Austerjost, Elias Knöchelmann, Thomas Kruse, Janina Kilian, Bastian Quaas, Michael W. Olszowy

    Published in SLAS Technology (2025-12-01)
    “…Conventionally, the initialization of new prototypes and concepts in laboratory automation and life science software applications has required close collaboration between hardware and software experts, as well as lab personnel such as biologists, chemists, biotechnologists, or process engineers. …”
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    Rapid exometabolome footprinting combined with multivariate statistics: A powerful tool for bioprocess optimization by Alexander Reiter, Lars Wesseling, Wolfgang Wiechert, Marco Oldiges

    Published in Engineering in Life Sciences (2025-02-01)
    “…In this work, we show how experimental setups such as miniature cultivation technology, dynamic and time‐optimized LC‐MS/MS metabolic footprinting tools, and automated workflows for the detection of local and global metabolic patterns can significantly accelerate bioprocess development. Potential media bottlenecks in form of phosphate and magnesium availability were identified by sensitivity analysis in parallelized microscale cultivation assisted by lab automation. …”
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    Metabolic Engineering of <i>Pediococcus acidilactici</i> BD16 for Heterologous Expression of Synthetic <i>alaD</i> Gene Cassette and L-Alanine Production in the Recombinant Strain... by Anshula Sharma, Masafumi Noda, Masanori Sugiyama, Baljinder Kaur, Ajaz Ahmad

    Published in Foods (2021-08-01)
    “…An efficient lab scale bioprocess was developed for high level fermentative production of L-alanine using metabolically engineered <i>Pediococcus acidilactici</i> BD16 (<i>alaD</i><sup>+</sup>). …”
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    Design-of-Experiment-Guided Establishment of a Fermentative Bioprocess for Biomass-Bound Astaxanthin with <i>Corynebacterium glutamicum</i> by Florian Meyer, Ina Schmitt, Thomas Schäffer, Volker F. Wendisch, Nadja A. Henke

    Published in Fermentation (2023-11-01)
    “…Notably, it naturally accumulates the carotenoid pigment decaprenoxanthin in its membranes. Metabolic engineering enabled the production of astaxanthin. Here, a bioprocess for astaxanthin production in lab-scale stirred bioreactors was established by a DoE-guided approach to optimize the basic process parameters pH, rDOS, aeration rate as well as inoculation cell density. …”
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