Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy

by Luengo, Alba, Sullivan, Lucas Bryan, Vander Heiden, Matthew G.
Published 2014

The importance of serine metabolism in cancer

by Mattaini, Katherine Ruth, Sullivan, Mark Robert, Vander Heiden, Matthew G.
Published 2017

Biochemical Underpinnings of Immune Cell Metabolic Phenotypes

by Olenchock, Benjamin A., Rathmell, Jeffrey C., Vander Heiden, Matthew G.
Published 2018

Metabolomic Biomarkers of Prostate Cancer: Prediction, Diagnosis, Progression, Prognosis, and Recurrence

by Kelly, R. S., Giovannucci, E., Mucci, L. A., Vander Heiden, Matthew G.
Published 2018

Emerging concepts: linking hypoxic signaling and cancer metabolism

by Lyssiotis, C A, Muñoz-Pinedo, C, Emerling, B M, Vander Heiden, Matthew G.
Published 2018

Cellular redox state constrains serine synthesis and nucleotide production to impact cell proliferation

by Diehl, Frances F., Lewis, Caroline A., Fiske, Brian Prescott, Vander Heiden, Matthew G.
Published 2020

Lack of Evidence for PKM2 Protein Kinase Activity

by Hosios, Aaron Marc, Fiske, Brian Prescott, Gui, Dan Yi, Vander Heiden, Matthew G.
Published 2016

Tumour Dormancy and Reawakening: Opportunities and Challenges

by Boire, Adrienne, Coffelt, Seth B., Quezada, Sergio A., Vander Heiden, Matthew G., Weeraratna, Ashani T.
Published 2020

Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting

by Alkan, H. Furkan, Luengo, Alba, Lau, Allison N., Lewis, Caroline A., Vander Heiden, Matthew G.
Published 2020

Increased PHGDH expression promotes aberrant melanin accumulation

by Mattaini, Katherine R., Sullivan, Mark R., Lau, Allison N., Fiske, Brian P., Vander Heiden, Matthew G.
Published 2020

Metabolic requirements for cancer cell proliferation

by Iliopoulos, Othon, Keibler, Mark Andrew, Wasylenko, Thomas Michael, Vander Heiden, Matthew G., Stephanopoulos, Gregory, Kelleher, Joanne Keene
Published 2018

Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition

by Lewis, Caroline A, Muir, Alexander, Danai, Laura V, Gui, Dan Yi, Waingarten, Chiara Y., Vander Heiden, Matthew G.
Published 2018

Cancer‐associated mutations in human pyruvate kinase M2 impair enzyme activity

by Liu, Vivian M., Howell, Andrea J., Hosios, Aaron M., Li, Zhaoqi, Israelsen, William J., Vander Heiden, Matthew G.
Published 2022

Cancer‐associated mutations in human pyruvate kinase M2 impair enzyme activity

by Liu, Vivian M., Howell, Andrea J., Hosios, Aaron M., Li, Zhaoqi, Israelsen, William J., Vander Heiden, Matthew G.
Published 2022

Antibody-Mediated Neutralization of Perfringolysin O for Intracellular Protein Delivery

by Yang, Nicole Jie Yeon, Sklaviadis, Demetra, Wittrup, Karl Dane, Gui, Dan Yi, Vander Heiden, Matthew G., Liu, David V.
Published 2016

Elevated circulating branched chain amino acids are an early event in pancreatic adenocarcinoma development

by Mayers, Jared R., Torrence, Margaret E., Fiske, Brian Prescott, Davidson, Shawn Michael, Papagiannakopoulos, Thales, Dayton, Talya Lucia, Vander Heiden, Matthew G.
Published 2015

An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation

by Kini, Mitali, Mattaini, Katherine Ruth, Davidson, Shawn Michael, Fiske, Brian Prescott, Vander Heiden, Matthew G., Brignole, Edward J, Drennan, Catherine L
Published 2015

Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State

by Garcia-Cao, Isabel, Song, Min Sup, Hobbs, Robin M, Laurent, Gaelle, Giorgi, Carlotta, de Boer, Vincent C. J., Anastasiou, Dimitrios, Ito, Keisuke, Sasaki, Atsuo T, Rameh, Lucia, Carracedo, Arkaitz, Vander Heiden, Matthew G, Cantley, Lewis C., Pinton, Paolo, Haigis, Marcia C., Pandolfi, Pier Paolo, Vander Heiden, Matthew G.
Published 2014

PKM2 is not required for pancreatic ductal adenocarcinoma

by Danai, Laura V, Di Vizio, Dolores, Hillis, Alissandra L., Lau, Allison N., Devoe, Camille X., Vander Heiden, Matthew G., Dayton, Talya Lucia
Published 2018

Heterogeneity of tumor-induced gene expression changes in the human metabolic network

by Hu, Jie, Locasale, Jason W., Bielas, Jason H., O'Sullivan, Jacintha, Sheahan, Kieran, Cantley, Lewis C., Vander Heiden, Matthew G., Vitkup, Dennis
Published 2014