Local Targeting of NAD + Salvage Pathway Alters the Immune Tumor Microenvironment and Enhances Checkpoint Immunotherapy in Glioblastoma

by Li, Ming, Kirtane, Ameya R, Kiyokawa, Juri, Nagashima, Hiroaki, Lopes, Aaron, Tirmizi, Zain A, Lee, Christine K, Traverso, Giovanni, Cahill, Daniel P, Wakimoto, Hiroaki
Published 2022

Improving D‐2‐hydroxyglutarate MR spectroscopic imaging in mutant isocitrate dehydrogenase glioma patients with multiplexed RF‐receive/B 0 ‐shim array coils a...

by Strasser, Bernhard, Arango, Nicolas S., Stockmann, Jason P., Gagoski, Borjan, Thapa, Bijaya, Li, Xianqi, Bogner, Wolfgang, Moser, Philipp, Small, Julia, Cahill, Daniel P., Batchelor, Tracy T., Dietrich, Jorg, Kouwe, Andre, White, Jacob, Adalsteinsson, Elfar, Andronesi, Ovidiu C.
Published 2022

Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma

by Braun, Christian J., Stanciu, Monica, Boutz, Paul L., Patterson, Jesse C., Calligaris, David, Higuchi, Fumi, Neupane, Rachit, Fenoglio, Silvia, Cahill, Daniel P., Wakimoto, Hiroaki, Agar, Nathalie Y.R, Yaffe, Michael B., Sharp, Phillip A., Hemann, Michael T., Lees, Jacqueline A., Boutz, Paul, Patterson, Jesse C, Yaffe, Michael B, Hemann, Michael, Lees, Jacqueline, Braun, Christian Joerg, Sharp, Phillip A.
Published 2018

Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

by Suvà, Mario L, Rheinbay, Esther, Gillespie, Shawn M, Patel, Anoop P, Wakimoto, Hiroaki, Rabkin, Samuel D, Riggi, Nicolo, Chi, Andrew S, Cahill, Daniel P, Nahed, Brian V, Curry, William T, Martuza, Robert L, Rivera, Miguel N, Rossetti, Nikki, Kasif, Simon, Beik, Samantha, Kadri, Sabah, Tirosh, Itay, Wortman, Ivo, Shalek, Alex K., Rozenblatt-Rosen, Orit, Regev, Aviv, Louis, David N, Bernstein, Bradley E
Published 2017

Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

by Prakadan, Sanjay M, Alvarez-Breckenridge, Christopher A, Markson, Samuel C, Kim, Albert E, Klein, Robert H, Nayyar, Naema, Navia, Andrew W, Kuter, Benjamin M, Kolb, Kellie E, Bihun, Ivanna, Mora, Joana L, Bertalan, Mia Solana, Shaw, Brian, White, Michael, Kaplan, Alexander, Stocking, Jackson H, Wadsworth, Marc H, Lee, Eudocia Q, Chukwueke, Ugonma, Wang, Nancy, Subramanian, Megha, Rotem, Denisse, Cahill, Daniel P, Adalsteinsson, Viktor A, Miller, Jeffrey W, Sullivan, Ryan J, Carter, Scott L, Brastianos, Priscilla K, Shalek, Alex K
Published 2022

Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma

by McBrayer, Samuel K., Mayers, Jared R., DiNatale, Gabriel J., Shi, Diana D., Khanal, Januka, Chakraborty, Abhishek A., Sarosiek, Kristopher A., Briggs, Kimberly J., Robbins, Alissa K., Sewastianik, Tomasz, Shareef, Sarah J., Olenchock, Benjamin A., Parker, Seth J., Tateishi, Kensuke, Spinelli, Jessica B., Islam, Mirazul, Haigis, Marcia C., Looper, Ryan E., Ligon, Keith L., Bernstein, Bradley E., Carrasco, Ruben D., Cahill, Daniel P., Asara, John M., Metallo, Christian M., Yennawar, Neela H., Vander Heiden, Matthew G., Kaelin, William G.
Published 2020

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq

by Venteicher, Andrew S., Tirosh, Itay, Hebert, Christine, Yizhak, Keren, Neftel, Cyril, Filbin, Mariella G., Hovestadt, Volker, Escalante, Leah E., Shaw, McKenzie L., Rodman, Christopher, Gillespie, Shawn M., Luo, Christina C., Ravichandran, Hiranmayi, Mylvaganam, Ravindra, Mount, Christopher, Onozato, Maristela L., Nahed, Brian V., Wakimoto, Hiroaki, Curry, William T., Iafrate, A. John, Rivera, Miguel N., Frosch, Matthew P., Brastianos, Priscilla K., Patel, Anoop P., Monje, Michelle, Cahill, Daniel P., Rozenblatt-Rosen, Orit, Louis, David N., Suvà, Mario L., Dionne, Danielle, Golub, Todd, Getz, Gad Asher, Regev, Aviv, Bernstein, Bradley E.
Published 2018

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

by Tirosh, Itay, Venteicher, Andrew S., Hebert, Christine, Escalante, Leah E., Patel, Anoop P., Yizhak, Keren, Fisher, Jonathan M., Rodman, Christopher, Mount, Christopher, Filbin, Mariella G., Neftel, Cyril, Desai, Niyati, Nyman, Jackson, Izar, Benjamin, Luo, Christina C., Francis, Joshua M., Patel, Aanand A., Onozato, Maristela L., Riggi, Nicolo, Livak, Kenneth J., Gennert, Dave, Satija, Rahul, Nahed, Brian V., Curry, William T., Martuza, Robert L., Mylvaganam, Ravindra, Iafrate, A. John, Frosch, Matthew P., Rivera, Miguel N., Getz, Gad, Rozenblatt-Rosen, Orit, Cahill, Daniel P., Monje, Michelle, Bernstein, Bradley E., Louis, David N., Suvà, Mario L., Golub, Todd, Regev, Aviv
Published 2018