Article C reactive protein adult alanine aminotransferase alanine aminotransferase blood level aspartate aminotransferase aspartate aminotransferase blood level caspase 3 cholesterol blood level controlled study cytokeratin 18 diabetes mellitus dyslipidemia enzyme linked immunosorbent assay fatty liver female high density lipoprotein cholesterol human hypertension liver fibrosis low density lipoprotein cholesterol major clinical study male metabolic syndrome X middle aged nonalcoholic fatty liver protein blood level sensitivity and specificity transient elastography triacylglycerol