Nonlinear ridge regression improves cell-type-specific differential expression analysis

by Fumihiko Takeuchi, Norihiro Kato
Published 2021-03-01

Complete sequencing of the bla(NDM-1)-positive IncA/C plasmid from Escherichia coli ST38 isolate suggests a possible origin from plant pathogens.

by Tsuyoshi Sekizuka, Mari Matsui, Kunikazu Yamane, Fumihiko Takeuchi, Makoto Ohnishi, Akira Hishinuma, Yoshichika Arakawa, Makoto Kuroda
Published 2011-01-01

Venous thromboembolism is caused by prothrombin p.Arg541Trp mutation in Japanese individuals

by Jumpei Yamamoto, Masaya Yamamoto, Kozue Takano, Toru Okazaki, Reiko Arakawa, Hisao Hara, Atsuko Okazaki, Fumihiko Takeuchi, Yukio Hiroi, Norihiro Kato
Published 2021-03-01

Integrative genomic analysis of blood pressure and related phenotypes in rats

by Fumihiko Takeuchi, Yi-Qiang Liang, Masato Isono, Michiko Tajima, Zong Hu Cui, Yoko Iizuka, Takanari Gotoda, Toru Nabika, Norihiro Kato
Published 2021-05-01

The Mitochondrial Genomes of a Myxozoan Genus Kudoa Are Extremely Divergent in Metazoa.

by Fumihiko Takeuchi, Tsuyoshi Sekizuka, Yumiko Ogasawara, Hiroshi Yokoyama, Ryoma Kamikawa, Yuji Inagaki, Tomoyoshi Nozaki, Yoshiko Sugita-Konishi, Takahiro Ohnishi, Makoto Kuroda
Published 2015-01-01

Amoebal endosymbiont Neochlamydia genome sequence illuminates the bacterial role in the defense of the host amoebae against Legionella pneumophila.

by Kasumi Ishida, Tsuyoshi Sekizuka, Kyoko Hayashida, Junji Matsuo, Fumihiko Takeuchi, Makoto Kuroda, Shinji Nakamura, Tomohiro Yamazaki, Mitsutaka Yoshida, Kaori Takahashi, Hiroki Nagai, Chihiro Sugimoto, Hiroyuki Yamaguchi
Published 2014-01-01

Correction: Genetic Variation of Human Papillomavirus Type 16 in Individual Clinical Specimens Revealed by Deep Sequencing

by Iwao Kukimoto, Tomohiko Maehama, Tsuyoshi Sekizuka, Yumiko Ogasawara, Kazunari Kondo, Rika Kusumoto-Matsuo, Seiichiro Mori, Yoshiyuki Ishii, Takamasa Takeuchi, Toshiyuki Yamaji, Fumihiko Takeuchi, Kentaro Hanada, Makoto Kuroda
Published 2014-01-01

Genetic variation of human papillomavirus type 16 in individual clinical specimens revealed by deep sequencing.

by Iwao Kukimoto, Tomohiko Maehama, Tsuyoshi Sekizuka, Yumiko Ogasawara, Kazunari Kondo, Rika Kusumoto-Matsuo, Seiichiro Mori, Yoshiyuki Ishii, Takamasa Takeuchi, Toshiyuki Yamaji, Fumihiko Takeuchi, Kentaro Hanada, Makoto Kuroda
Published 2013-01-01

Correction: Genetic Variation of Human Papillomavirus Type 16 in Individual Clinical Specimens Revealed by Deep Sequencing.

by Iwao Kukimoto, Tomohiko Maehama, Tsuyoshi Sekizuka, Yumiko Ogasawara, Kazunari Kondo, Rika Kusumoto-Matsuo, Seiichiro Mori, Yoshiyuki Ishii, Takamasa Takeuchi, Toshiyuki Yamaji, Fumihiko Takeuchi, Kentaro Hanada, Makoto Kuroda
Published 2014-01-01

Molecular and biological analysis revealed genetic diversity and high virulence strain of Toxoplasma gondii in Japan.

by Junpei Fukumoto, Akinori Yamano, Motomichi Matsuzaki, Hisako Kyan, Tatsunori Masatani, Tomohide Matsuo, Toshihiro Matsui, Mami Murakami, Yasuhiro Takashima, Ryuma Matsubara, Michiru Tahara, Takaya Sakura, Fumihiko Takeuchi, Kisaburo Nagamune
Published 2020-01-01

Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals.

by Fumihiko Takeuchi, Masato Isono, Tomohiro Katsuya, Mitsuhiro Yokota, Ken Yamamoto, Toru Nabika, Kazuro Shimokawa, Eitaro Nakashima, Takao Sugiyama, Hiromi Rakugi, Shuhei Yamaguchi, Toshio Ogihara, Yukio Yamori, Norihiro Kato
Published 2012-01-01

Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction.

by Yuta Tsukamoto, Sotaro Ikeda, Koji Uwai, Riho Taguchi, Kazuaki Chayama, Takemasa Sakaguchi, Ryo Narita, Wan-Ling Yao, Fumihiko Takeuchi, Yukie Otakaki, Koichi Watashi, Takaji Wakita, Hiroki Kato, Takashi Fujita
Published 2018-01-01

Protochlamydia induces apoptosis of human HEp-2 cells through mitochondrial dysfunction mediated by chlamydial protease-like activity factor.

by Junji Matsuo, Shinji Nakamura, Atsushi Ito, Tomohiro Yamazaki, Kasumi Ishida, Yasuhiro Hayashi, Mitsutaka Yoshida, Kaori Takahashi, Tsuyoshi Sekizuka, Fumihiko Takeuchi, Makoto Kuroda, Hiroki Nagai, Kyoko Hayashida, Chihiro Sugimoto, Hiroyuki Yamaguchi
Published 2013-01-01

Molecular evolution of hemagglutinin (H) gene in measles virus genotypes D3, D5, D9, and H1.

by Mika Saitoh, Makoto Takeda, Koichi Gotoh, Fumihiko Takeuchi, Tsuyoshi Sekizuka, Makoto Kuroda, Katsumi Mizuta, Akihide Ryo, Ryota Tanaka, Haruyuki Ishii, Hayato Takada, Kunihisa Kozawa, Ayako Yoshida, Masahiro Noda, Nobuhiko Okabe, Hirokazu Kimura
Published 2012-01-01

A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.

by Fumihiko Takeuchi, Ralph McGinnis, Stephane Bourgeois, Chris Barnes, Niclas Eriksson, Nicole Soranzo, Pamela Whittaker, Venkatesh Ranganath, Vasudev Kumanduri, William McLaren, Lennart Holm, Jonatan Lindh, Anders Rane, Mia Wadelius, Panos Deloukas
Published 2009-03-01

Deletion of CDKAL1 affects high-fat diet-induced fat accumulation and glucose-stimulated insulin secretion in mice, indicating relevance to diabetes.

by Tadashi Okamura, Rieko Yanobu-Takanashi, Fumihiko Takeuchi, Masato Isono, Koichi Akiyama, Yukiko Shimizu, Motohito Goto, Yi-Qiang Liang, Ken Yamamoto, Tomohiro Katsuya, Akihiro Fujioka, Keizo Ohnaka, Ryoichi Takayanagi, Toshio Ogihara, Yukio Yamori, Norihiro Kato
Published 2012-01-01

Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor.

by Fumihiko Takeuchi, Sotaro Ikeda, Yuta Tsukamoto, Yoshikazu Iwasawa, Chen Qihao, Yukie Otakaki, Ouda Ryota, Wan-Ling Yao, Ryo Narita, Hijikata Makoto, Koichi Watashi, Takaji Wakita, Koh Takeuchi, Kazuaki Chayama, Amane Kogure, Hiroki Kato, Takashi Fujita
Published 2019-01-01

The fine-scale genetic structure and evolution of the Japanese population.

by Fumihiko Takeuchi, Tomohiro Katsuya, Ryosuke Kimura, Toru Nabika, Minoru Isomura, Takayoshi Ohkubo, Yasuharu Tabara, Ken Yamamoto, Mitsuhiro Yokota, Xuanyao Liu, Woei-Yuh Saw, Dolikun Mamatyusupu, Wenjun Yang, Shuhua Xu, Japanese Genome Variation Consortium, Yik-Ying Teo, Norihiro Kato
Published 2017-01-01

Systematic fine-mapping of association with BMI and type 2 diabetes at the FTO locus by integrating results from multiple ethnic groups.

by Koichi Akiyama, Fumihiko Takeuchi, Masato Isono, Sureka Chakrawarthy, Quang Ngoc Nguyen, Wanqing Wen, Ken Yamamoto, Tomohiro Katsuya, Anuradhani Kasturiratne, Son Thai Pham, Wei Zheng, Yumi Matsushita, Miyako Kishimoto, Loi Doan Do, Xiao-Ou Shu, Ananda R Wickremasinghe, Hiroshi Kajio, Norihiro Kato
Published 2014-01-01

Interethnic analyses of blood pressure loci in populations of East Asian and European descent

by Fumihiko Takeuchi, Masato Akiyama, Nana Matoba, Tomohiro Katsuya, Masahiro Nakatochi, Yasuharu Tabara, Akira Narita, Woei-Yuh Saw, Sanghoon Moon, Cassandra N. Spracklen, Jin-Fang Chai, Young-Jin Kim, Liang Zhang, Chaolong Wang, Huaixing Li, Honglan Li, Jer-Yuarn Wu, Rajkumar Dorajoo, Jovia L. Nierenberg, Ya Xing Wang, Jing He, Derrick A. Bennett, Atsushi Takahashi, Yukihide Momozawa, Makoto Hirata, Koichi Matsuda, Hiromi Rakugi, Eitaro Nakashima, Masato Isono, Matsuyuki Shirota, Atsushi Hozawa, Sahoko Ichihara, Tatsuaki Matsubara, Ken Yamamoto, Katsuhiko Kohara, Michiya Igase, Sohee Han, Penny Gordon-Larsen, Wei Huang, Nanette R. Lee, Linda S. Adair, Mi Yeong Hwang, Juyoung Lee, Miao Li Chee, Charumathi Sabanayagam, Wanting Zhao, Jianjun Liu, Dermot F. Reilly, Liang Sun, Shaofeng Huo, Todd L. Edwards, Jirong Long, Li-Ching Chang, Chien-Hsiun Chen, Jian-Min Yuan, Woon-Puay Koh, Yechiel Friedlander, Tanika N. Kelly, Wen Bin Wei, Liang Xu, Hui Cai, Yong-Bing Xiang, Kuang Lin, Robert Clarke, Robin G. Walters, Iona Y. Millwood, Liming Li, John C. Chambers, Jaspal S. Kooner, Paul Elliott, Pim van der Harst, The International Genomics of Blood Pressure (iGEN-BP) Consortium, Zhengming Chen, Makoto Sasaki, Xiao-Ou Shu, Jost B. Jonas, Jiang He, Chew-Kiat Heng, Yuan-Tsong Chen, Wei Zheng, Xu Lin, Yik-Ying Teo, E-Shyong Tai, Ching-Yu Cheng, Tien Yin Wong, Xueling Sim, Karen L. Mohlke, Masayuki Yamamoto, Bong-Jo Kim, Tetsuro Miki, Toru Nabika, Mitsuhiro Yokota, Yoichiro Kamatani, Michiaki Kubo, Norihiro Kato
Published 2018-11-01