Interdisciplinary Profile: An Established Chemist Journeys into Different Disciplines

by James R. Heath
Published 2020-05-01

A cocktail of thermally stable, chemically synthesized capture agents for the efficient detection of anti-gp41 antibodies from human sera.

by Jessica A Pfeilsticker, Aiko Umeda, Blake Farrow, Connie L Hsueh, Kaycie M Deyle, Jocelyn T Kim, Bert T Lai, James R Heath
Published 2013-01-01

A kinetic investigation of interacting, stimulated T cells identifies conditions for rapid functional enhancement, minimal phenotype differentiation, and improved adoptive cell tra...

by Jing Zhou, Michael T Bethune, Natalia Malkova, Alexander M Sutherland, Begonya Comin-Anduix, Yapeng Su, David Baltimore, Antoni Ribas, James R Heath
Published 2018-01-01

Phenotypic heterogeneity and evolution of melanoma cells associated with targeted therapy resistance.

by Yapeng Su, Marcus Bintz, Yezi Yang, Lidia Robert, Alphonsus H C Ng, Victoria Liu, Antoni Ribas, James R Heath, Wei Wei
Published 2019-06-01

Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells

by Jiajun Du, Yapeng Su, Chenxi Qian, Dan Yuan, Kun Miao, Dongkwan Lee, Alphonsus H. C. Ng, Reto S. Wijker, Antoni Ribas, Raphael D. Levine, James R. Heath, Lu Wei
Published 2020-09-01

Domain-swapped T cell receptors improve the safety of TCR gene therapy

by Michael T Bethune, Marvin H Gee, Mario Bunse, Mark S Lee, Eric H Gschweng, Meghana S Pagadala, Jing Zhou, Donghui Cheng, James R Heath, Donald B Kohn, Michael S Kuhns, Wolfgang Uckert, David Baltimore
Published 2016-11-01

Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1

by Yue Lu, Alphonsus H. C. Ng, Frances E. Chow, Richard G. Everson, Beth A. Helmink, Michael T. Tetzlaff, Rohit Thakur, Jennifer A. Wargo, Timothy F. Cloughesy, Robert M. Prins, James R. Heath
Published 2021-06-01

Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line

by Yapeng Su, Melissa E. Ko, Hanjun Cheng, Ronghui Zhu, Min Xue, Jessica Wang, Jihoon W. Lee, Luke Frankiw, Alexander Xu, Stephanie Wong, Lidia Robert, Kaitlyn Takata, Dan Yuan, Yue Lu, Sui Huang, Antoni Ribas, Raphael Levine, Garry P. Nolan, Wei Wei, Sylvia K. Plevritis, Guideng Li, David Baltimore, James R. Heath
Published 2020-05-01

Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood

by Songming Peng, Jesse M. Zaretsky, Alphonsus H.C. Ng, William Chour, Michael T. Bethune, Jongchan Choi, Alice Hsu, Elizabeth Holman, Xiaozhe Ding, Katherine Guo, Jungwoo Kim, Alexander M. Xu, John E. Heath, Won Jun Noh, Jing Zhou, Yapeng Su, Yue Lu, Jami McLaughlin, Donghui Cheng, Owen N. Witte, David Baltimore, Antoni Ribas, James R. Heath
Published 2019-09-01