Proof of Principle that Molecular Modeling Followed by a Biophysical Experiment Can Develop Small Molecules that Restore Function to the Cardiac Thin Filament in the Presence of Ca...

by Lukasz Szatkowski, Melissa L. Lynn, Teryn Holeman, Michael R. Williams, Anthony P. Baldo, Jil C. Tardiff, Steven D. Schwartz
Published 2019-04-01

In Vivo Cannulation Methods for Cardiomyocytes Isolation from Heart Disease Models.

by Zhong Jian, Yi-Je Chen, Rafael Shimkunas, Yuwen Jian, Mark Jaradeh, Karen Chavez, Nipavan Chiamvimonvat, Jil C Tardiff, Leighton T Izu, Robert S Ross, Ye Chen-Izu
Published 2016-01-01

Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts

by Joseph D. Powers, Kristina B. Kooiker, Allison B. Mason, Abigail E. Teitgen, Galina V. Flint, Jil C. Tardiff, Steven D. Schwartz, Andrew D. McCulloch, Michael Regnier, Jennifer Davis, Farid Moussavi-Harami
Published 2020-10-01

Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response

by Shamim A. K. Chowdhury, Chad M. Warren, Jillian N. Simon, David M. Ryba, Ashley Batra, Peter Varga, Evangelia G. Kranias, Jil C. Tardiff, R. John Solaro, Beata M. Wolska, Beata M. Wolska
Published 2020-03-01

Differences in microRNA-29 and Pro-fibrotic Gene Expression in Mouse and Human Hypertrophic Cardiomyopathy

by Yamin Liu, Yamin Liu, Junaid Afzal, Junaid Afzal, Styliani Vakrou, Gabriela V. Greenland, Gabriela V. Greenland, C. Conover Talbot, Virginia B. Hebl, Yufan Guan, Rehan Karmali, Jil C. Tardiff, Leslie A. Leinwand, Jeffrey E. Olgin, Samarjit Das, Ryuya Fukunaga, M. Roselle Abraham, M. Roselle Abraham
Published 2019-12-01