The effects of age and systemic metabolism on anti-tumor T cell responses

by Jefte M Drijvers, Arlene H Sharpe, Marcia C Haigis
Published 2020-11-01

An LC-MS Approach to Quantitative Measurement of Ammonia Isotopologues

by Jessica B. Spinelli, Liam P. Kelley, Marcia C. Haigis
Published 2017-09-01

Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity.

by Lydia W S Finley, Wilhelm Haas, Valérie Desquiret-Dumas, Douglas C Wallace, Vincent Procaccio, Steven P Gygi, Marcia C Haigis
Published 2011-01-01

T Cell Activation Depends on Extracellular Alanine

by Noga Ron-Harel, Jonathan M. Ghergurovich, Giulia Notarangelo, Martin W. LaFleur, Yoshiki Tsubosaka, Arlene H. Sharpe, Joshua D. Rabinowitz, Marcia C. Haigis
Published 2019-09-01

l-Alanine activates hepatic AMP-activated protein kinase and modulates systemic glucose metabolism

by Yusuke Adachi, Ana Luisa De Sousa-Coelho, Ikue Harata, Charlie Aoun, Sandra Weimer, Xu Shi, Karina N. Gonzalez Herrera, Hirokazu Takahashi, Chris Doherty, Yasushi Noguchi, Laurie J. Goodyear, Marcia C. Haigis, Robert E. Gerszten, Mary-Elizabeth Patti
Published 2018-11-01

SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis

by Elma Zaganjor, Haejin Yoon, Jessica B. Spinelli, Elizabeth R. Nunn, Gaëlle Laurent, Paulina Keskinidis, Suganja Sivaloganathan, Shakchhi Joshi, Giulia Notarangelo, Stacy Mulei, Mathew T. Chvasta, Sarah A. Tucker, Krystle Kalafut, Robert A.H. van de Ven, Clary B. Clish, Marcia C. Haigis
Published 2021-07-01

Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3

by Karina N. Gonzalez Herrera, Elma Zaganjor, Yoshinori Ishikawa, Jessica B. Spinelli, Haejin Yoon, Jia-Ren Lin, F. Kyle Satterstrom, Alison Ringel, Stacy Mulei, Amanda Souza, Joshua M. Gorham, Craig C. Benson, Jonathan G. Seidman, Peter K. Sorger, Clary B. Clish, Marcia C. Haigis
Published 2018-02-01

Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway

by Sarah E. Smith, Xiaoying Chen, Lindsey M. Brier, Jonathan R. Bumstead, Nicholas R. Rensing, Alison E. Ringel, Haewon Shin, Anna Oldenborg, Jan R. Crowley, Annie R. Bice, Krikor Dikranian, Joseph E. Ippolito, Marcia C. Haigis, Thomas Papouin, Guoyan Zhao, Michael Wong, Joseph P. Culver, Azad Bonni
Published 2020-12-01

Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia

by Barry M. Zee, Kamrine E. Poels, Cong-Hui Yao, Kimihito C. Kawabata, Gongwei Wu, Cihangir Duy, William D. Jacobus, Elizabeth Senior, Jennifer E. Endress, Ashwini Jambhekar, Scott B. Lovitch, Jiexian Ma, Abhinav Dhall, Isaac S. Harris, M. Andres Blanco, David B. Sykes, Jonathan D. Licht, David M. Weinstock, Ari Melnick, Marcia C. Haigis, Franziska Michor, Yang Shi
Published 2021-06-01