Amniotic epithelial cells: a new tool to combat aging and age-related diseases?

by Clara Di Germanio, Clara Di Germanio, Michel Bernier, Rafael de Cabo, Barbara Barboni
Published 2016-11-01

Cell survival from chemotherapy depends on NF-kappaB transcriptional up-regulation of coenzyme Q biosynthesis.

by Gloria Brea-Calvo, Emilio Siendones, José A Sánchez-Alcázar, Rafael de Cabo, Plácido Navas
Published 2009-01-01

JNK1 phosphorylates SIRT1 and promotes its enzymatic activity.

by Nargis Nasrin, Virendar K Kaushik, Eric Fortier, Daniel Wall, Kevin J Pearson, Rafael de Cabo, Laura Bordone
Published 2009-12-01

Energy Restriction and Colorectal Cancer: A Call for Additional Research

by Maria Castejón, Adrian Plaza, Jorge Martinez-Romero, Pablo Jose Fernandez-Marcos, Rafael de Cabo, Alberto Diaz-Ruiz
Published 2020-01-01

RAP1 Protects from Obesity through Its Extratelomeric Role Regulating Gene Expression

by Paula Martínez, Gonzalo Gómez-López, Fernando García, Evi Mercken, Sarah Mitchell, Juana M. Flores, Rafael de Cabo, Maria A. Blasco
Published 2013-06-01

RAP1 Protects from Obesity through Its Extratelomeric Role Regulating Gene Expression

by Paula Martínez, Gonzalo Gómez-López, Fernando García, Evi Mercken, Sarah Mitchell, Juana M. Flores, Rafael de Cabo, Maria A. Blasco
Published 2013-07-01

In vitro cellular adaptations of indicators of longevity in response to treatment with serum collected from humans on calorie restricted diets.

by Joanne S Allard, Leonie K Heilbronn, Carolina Smith, Nicole D Hunt, Donald K Ingram, Eric Ravussin, Pennington CALERIE Team, Rafael de Cabo
Published 2008-09-01

A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylation

by David Siegel, Stephanie Bersie, Peter Harris, Andrea Di Francesco, Michael Armstrong, Nichole Reisdorph, Michel Bernier, Rafael de Cabo, Kristofer Fritz, David Ross
Published 2021-02-01

Redox modulation of NQO1.

by David Siegel, Donna D Dehn, Samantha S Bokatzian, Kevin Quinn, Donald S Backos, Andrea Di Francesco, Michel Bernier, Nichole Reisdorph, Rafael de Cabo, David Ross
Published 2018-01-01

Oxidative stress accumulates in adipose tissue during aging and inhibits adipogenesis.

by Hannes M Findeisen, Kevin J Pearson, Florence Gizard, Yue Zhao, Hua Qing, Karrie L Jones, Dianne Cohn, Elizabeth B Heywood, Rafael de Cabo, Dennis Bruemmer
Published 2011-04-01

Caloric restriction improves health and survival of rhesus monkeys

by Julie A. Mattison, Ricki J. Colman, T. Mark Beasley, David B. Allison, Joseph W. Kemnitz, George S. Roth, Donald K. Ingram, Richard Weindruch, Rafael de Cabo, Rozalyn M. Anderson
Published 2017-01-01

Discoidin domain Receptor 2: A determinant of metabolic syndrome-associated arterial fibrosis in non-human primates.

by Mereena George Ushakumary, Mingyi Wang, Harikrishnan V, Allen Sam Titus, Jing Zhang, Lijuan Liu, Robert Monticone, Yushi Wang, Julie A Mattison, Rafael de Cabo, Edward G Lakatta, Shivakumar Kailasam
Published 2019-01-01

A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin

by Morgan Levine, Ross A McDevitt, Margarita Meer, Kathy Perdue, Andrea Di Francesco, Theresa Meade, Colin Farrell, Kyra Thrush, Meng Wang, Christopher Dunn, Matteo Pellegrini, Rafael de Cabo, Luigi Ferrucci
Published 2020-11-01

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.

by Ron Firestein, Gil Blander, Shaday Michan, Philipp Oberdoerffer, Shuji Ogino, Jennifer Campbell, Anupama Bhimavarapu, Sandra Luikenhuis, Rafael de Cabo, Charles Fuchs, William C Hahn, Leonard P Guarente, David A Sinclair
Published 2008-04-01

Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice

by Samantha M. Solon-Biet, Sarah J. Mitchell, Sean C.P. Coogan, Victoria C. Cogger, Rahul Gokarn, Aisling C. McMahon, David Raubenheimer, Rafael de Cabo, Stephen J. Simpson, David G. Le Couteur
Published 2015-06-01

Conserved and differential effects of dietary energy intake on the hippocampal transcriptomes of females and males.

by Bronwen Martin, Michele Pearson, Randall Brenneman, Erin Golden, Alex Keselman, Titilola Iyun, Olga D Carlson, Josephine M Egan, Kevin G Becker, William Wood, Vinayakumar Prabhu, Rafael de Cabo, Stuart Maudsley, Mark P Mattson
Published 2008-06-01

Health benefits of late-onset metformin treatment every other week in mice

by Irene Alfaras, Sarah J. Mitchell, Hector Mora, Darisbeth Rosario Lugo, Alessandra Warren, Ignacio Navas-Enamorado, Vickie Hoffmann, Christopher Hine, James R. Mitchell, David G. Le Couteur, Victoria C. Cogger, Michel Bernier, Rafael de Cabo
Published 2017-11-01

Loss of miR-451a enhances SPARC production during myogenesis.

by Rachel Munk, Jennifer L Martindale, Xiaoling Yang, Jen-Hao Yang, Ioannis Grammatikakis, Clara Di Germanio, Sarah J Mitchell, Rafael de Cabo, Elin Lehrmann, Yongqing Zhang, Kevin G Becker, Vered Raz, Myriam Gorospe, Kotb Abdelmohsen, Amaresh C Panda
Published 2019-01-01

Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance

by Nathan L. Price, Abhishek K. Singh, Noemi Rotllan, Leigh Goedeke, Allison Wing, Alberto Canfrán-Duque, Alberto Diaz-Ruiz, Elisa Araldi, Ángel Baldán, Joao-Paulo Camporez, Yajaira Suárez, Matthew S. Rodeheffer, Gerald I. Shulman, Rafael de Cabo, Carlos Fernández-Hernando
Published 2018-02-01

Pomalidomide Reduces Ischemic Brain Injury in Rodents

by Yan-Rou Tsai, David Tweedie, Ignacio Navas-Enamorado, Michael T. Scerba, Cheng-Fu Chang, Jing-Huei Lai, John Chung-Che Wu, Yen-Hua Chen, Shuo-Jhen Kang, Barry J. Hoffer, Rafael de Cabo, Nigel H. Greig, Yung-Hsiao Chiang, Kai-Yun Chen
Published 2019-04-01