Key Challenges in Rheumatic and Musculoskeletal Disease Translational Research

by Ursula Fearon, Douglas J. Veale
Published 2014-12-01

The PD-1:PD-L1 axis in Inflammatory Arthritis

by Mary Canavan, Achilleas Floudas, Douglas J. Veale, Ursula Fearon
Published 2021-01-01

STAT3 Mediates the Differential Effects of Oncostatin M and TNFα on RA Synovial Fibroblast and Endothelial Cell Function

by Megan M. Hanlon, Tatsiana Rakovich, Clare C. Cunningham, Sharon Ansboro, Douglas J. Veale, Ursula Fearon, Ursula Fearon, Trudy McGarry, Trudy McGarry
Published 2019-08-01

Functionally Mature CD1c+ Dendritic Cells Preferentially Accumulate in the Inflammatory Arthritis Synovium

by Mary Canavan, Mary Canavan, Viviana Marzaioli, Viviana Marzaioli, Vipul Bhargava, Sunil Nagpal, Phil Gallagher, Conor Hurson, Ronan Mullan, Douglas J. Veale, Ursula Fearon, Ursula Fearon
Published 2021-10-01

Targeting JAK-STAT Signalling Alters PsA Synovial Fibroblast Pro-Inflammatory and Metabolic Function

by Aisling O’Brien, Aisling O’Brien, Megan Mary Hanlon, Megan Mary Hanlon, Viviana Marzaioli, Viviana Marzaioli, Siobhan C. Wade, Siobhan C. Wade, Keelin Flynn, Ursula Fearon, Ursula Fearon, Douglas J. Veale
Published 2021-06-01

Association of the Rheumatoid Arthritis Severity Variant rs26232 with the Invasive Activity of Synovial Fibroblasts

by Emma R Dorris, Eimear Linehan, Michelle Trenkmann, Douglas J Veale, Ursula Fearon, Anthony G. Wilson
Published 2019-10-01

Monocyte-Derived Dendritic Cell Differentiation in Inflammatory Arthritis Is Regulated by the JAK/STAT Axis via NADPH Oxidase Regulation

by Viviana Marzaioli, Mary Canavan, Achilleas Floudas, Siobhan C. Wade, Candice Low, Douglas J. Veale, Ursula Fearon
Published 2020-07-01

ACPA Status Correlates with Differential Immune Profile in Patients with Rheumatoid Arthritis

by Achilleas Floudas, Mary Canavan, Trudy McGarry, Ronan Mullan, Sunil Nagpal, Douglas J. Veale, Ursula Fearon
Published 2021-03-01

Serum miRNA Signature in Rheumatoid Arthritis and “At-Risk Individuals”

by Clare C. Cunningham, Clare C. Cunningham, Sarah Wade, Sarah Wade, Achilleas Floudas, Achilleas Floudas, Carl Orr, Trudy McGarry, Trudy McGarry, Siobhan Wade, Siobhan Wade, Sian Cregan, Ursula Fearon, Ursula Fearon, Douglas J. Veale
Published 2021-03-01

Toll-like receptor 2 induced angiogenesis and invasion is mediated through the Tie2 signalling pathway in rheumatoid arthritis.

by Tajvur Saber, Douglas J Veale, Emese Balogh, Jennifer McCormick, Sinead NicAnUltaigh, Mary Connolly, Ursula Fearon
Published 2011-01-01

Long-term remission and biologic persistence rates: 12-year real-world data

by Kieran Murray, Matthew Turk, Yousef Alammari, Francis Young, Phil Gallagher, Tajvur Saber, Ursula Fearon, Douglas J. Veale
Published 2021-01-01

The Utility and Limitations of CRP, ESR and DAS28-CRP in Appraising Disease Activity in Rheumatoid Arthritis

by Carl K. Orr, Aurelie Najm, Francis Young, Trudy McGarry, Monika Biniecka, Ursula Fearon, Douglas J. Veale
Published 2018-08-01

Oxidative stress impairs energy metabolism in primary cells and synovial tissue of patients with rheumatoid arthritis

by Emese Balogh, Douglas J. Veale, Trudy McGarry, Carl Orr, Zoltan Szekanecz, Chin-Teck Ng, Ursula Fearon, Monika Biniecka
Published 2018-05-01

The effects of alcohol consumption and its associations with disease activity among 979 patients with inflammatory arthritis

by Phil Gallagher, Ursula Fearon, Sinead Maguire, Matthew Turk, Yousef Alammari, Aine Gorman, Francis Young, Tajvur Saber, Lorna Freeman, Finbar O’Shea
Published 2021-08-01

Differential expression of NK receptors CD94 and NKG2A by T cells in rheumatoid arthritis patients in remission compared to active disease.

by Ceara E Walsh, Elizabeth J Ryan, Cliona O'Farrelly, Lucy Golden-Mason, Oliver FitzGerald, Douglas J Veale, Barry Bresnihan, Ursula Fearon
Published 2011-01-01

IL-17A expression is localised to both mononuclear and polymorphonuclear synovial cell infiltrates.

by Ellen M Moran, René Heydrich, Chin Teck Ng, Tajvur P Saber, Jennifer McCormick, Joachim Sieper, Heiner Appel, Ursula Fearon, Douglas J Veale
Published 2011-01-01

Pathogenic, glycolytic PD-1+ B cells accumulate in the hypoxic RA joint

by Achilleas Floudas, Nuno Neto, Viviana Marzaioli, Kieran Murray, Barry Moran, Michael G. Monaghan, Candice Low, Ronan H. Mullan, Navin Rao, Vinod Krishna, Sunil Nagpal, Douglas J. Veale, Ursula Fearon
Published 2020-11-01

Dysregulated miR-125a promotes angiogenesis through enhanced glycolysisResearch in context

by Sarah M. Wade, Nils Ohnesorge, Hayley McLoughlin, Monika Biniecka, Steven P. Carter, Michelle Trenkman, Clare C. Cunningham, Trudy McGarry, Mary Canavan, Breandán N. Kennedy, Douglas J. Veale, Ursula Fearon
Published 2019-09-01

Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus erythematosus

by Suzanne Cole, Alice Walsh, Xuefeng Yin, Mihir D. Wechalekar, Malcolm D. Smith, Susanna M. Proudman, Douglas J. Veale, Ursula Fearon, Costantino Pitzalis, Frances Humby, Michele Bombardieri, Amy Axel, Homer Adams, Christopher Chiu, Michael Sharp, John Alvarez, Ian Anderson, Loui Madakamutil, Sunil Nagpal, Yanxia Guo
Published 2018-05-01

Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression.

by Yanxia Guo, Alice M Walsh, Mary Canavan, Mihir D Wechalekar, Suzanne Cole, Xuefeng Yin, Brittney Scott, Mathew Loza, Carl Orr, Trudy McGarry, Michele Bombardieri, Frances Humby, Susanna M Proudman, Costantino Pitzalis, Malcolm D Smith, Joshua R Friedman, Ian Anderson, Loui Madakamutil, Douglas J Veale, Ursula Fearon, Sunil Nagpal
Published 2018-01-01