Protein O-Fucosyltransferase 2 Is Not Essential for Plasmodium berghei Development

Protein O-Fucosyltransferase 2 Is Not Essential for Plasmodium berghei Development

Thrombospondin type I repeat (TSR) domains are commonly O-fucosylated by protein O-fucosyltransferase 2 (PoFUT2), and this modification is required for optimal folding and secretion of TSR-containing proteins. The human malaria parasite Plasmodium falciparum expresses proteins containing TSR domains...

Full description

Bibliographic Details
Main Authors: Silvia Sanz, Eleonora Aquilini, Rebecca E. Tweedell, Garima Verma, Timothy Hamerly, Bernadette Hritzo, Abhai Tripathi, Marta Machado, Thomas S. Churcher, João A. Rodrigues, Luis Izquierdo, Rhoel R. Dinglasan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Plasmodium falciparum
Plasmodium berghei
O-fucosylation
protein O-fucosyltransferase 2
oocyst
sporozoite
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00238/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00238/full

Similar Items