Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.

<h4>Background</h4>Circulating lipoprotein lipids cause coronary heart disease (CHD). However, the precise way in which one or more lipoprotein lipid-related entities account for this relationship remains unclear. Using genetic instruments for lipoprotein lipid traits implemented through...

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Bibliographic Details
Main Authors: Tom G Richardson, Eleanor Sanderson, Tom M Palmer, Mika Ala-Korpela, Brian A Ference, George Davey Smith, Michael V Holmes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1003062