CHO Quasispecies—Implications for Manufacturing Processes
Chinese hamster ovary (CHO) cells are a source of multi-ton quantities of protein pharmaceuticals. They are, however, immortalized cells, characterized by a high degree of genetic and phenotypic diversity. As is known for any biological system, this diversity is enhanced by selective forces when lab...
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| Format: | Article |
| Language: | English |
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MDPI AG
2013-10-01
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| Series: | Processes |
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| Online Access: | http://www.mdpi.com/2227-9717/1/3/296 |