ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

Abstract Background The ETS transcription factor ETV4 is involved in the main steps of organogenesis and is also a significant mediator of tumorigenesis and metastasis, such as in breast cancer. Indeed, ETV4 is overexpressed in breast tumors and is associated with distant metastasis and poor prognos...

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Bibliographic Details
Main Authors: Mandy Dumortier, Franck Ladam, Isabelle Damour, Sophie Vacher, Ivan Bièche, Nathalie Marchand, Yvan de Launoit, David Tulasne, Anne Chotteau-Lelièvre
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Breast Cancer Research
Subjects:
ETV4
Transcription factor
MMP13
Tumorigenesis
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s13058-018-0992-0

Internet

http://link.springer.com/article/10.1186/s13058-018-0992-0

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