Sample size requirements for separating out the effects of combination treatments: Randomised controlled trials of combination therapy vs. standard treatment compared to factorial designs for patients with tuberculous meningitis
<p>Abstract</p> <p>Background</p> <p>In certain diseases clinical experts may judge that the intervention with the best prospects is the addition of two treatments to the standard of care. This can either be tested with a simple randomized trial of combination versus st...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-02-01
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Series: | Trials |
Online Access: | http://www.trialsjournal.com/content/12/1/26 |