Generation of an induced pluripotent stem cell line from an individual with a heterozygous RECQL4 mutation

The DNA helicase RECQL4 is known for its roles in DNA replication and repair. RECQL4 mutations cause several genetic disorders including Rothmund-Thomson syndrome (RTS), characterized by developmental defects and predisposition to osteosarcoma. Here we reprogrammed fibroblasts with a heterozygous RE...

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Bibliographic Details
Main Authors:	Brittany E. Jewell, Mo Liu, Linchao Lu, Ruoji Zhou, Jian Tu, Dandan Zhu, Zijun Huo, An Xu, Donghui Wang, Helen Mata, Weidong Jin, Weiya Xia, Pulivarthi H. Rao, Ruiying Zhao, Mien-Chie Hung, Lisa L. Wang, Dung-Fang Lee
Format:	Article
Language:	English
Published:	Elsevier 2018-12-01
Series:	Stem Cell Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S1873506118302447

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http://www.sciencedirect.com/science/article/pii/S1873506118302447

Generation of an induced pluripotent stem cell line from an individual with a heterozygous RECQL4 mutation

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