Antiplasmodial Activity, Cytotoxicity and Structure-Activity Relationship Study of Cyclopeptide Alkaloids

Cyclopeptide alkaloids are polyamidic, macrocyclic compounds, containing a 13-, 14-, or 15-membered ring. The ring system consists of a hydroxystyrylamine moiety, an amino acid, and a β-hydroxy amino acid; attached to the ring is a side chain, comprised of one or two more amino acid moieties. In vit...

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Bibliographic Details
Main Authors: Emmy Tuenter, Karen Segers, Kyo Bin Kang, Johan Viaene, Sang Hyun Sung, Paul Cos, Louis Maes, Yvan Vander Heyden, Luc Pieters
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Molecules
Subjects:
SAR
Online Access:http://www.mdpi.com/1420-3049/22/2/224