Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development
SUMMARY Neurofibromatosis type 1 (NF1) is a common, dominantly inherited genetic disorder that results from mutations in the neurofibromin 1 (NF1) gene. Affected individuals demonstrate abnormalities in neural-crest-derived tissues that include hyperpigmented skin lesions and benign peripheral nerve...
Main Authors: | , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2012-11-01
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Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/5/6/881 |