Selective targeting of mRNA and the following protein synthesis of CaMKIIα at the long-term potentiation-induced site

Selective targeting of mRNA and the following protein synthesis of CaMKIIα at the long-term potentiation-induced site

Late-phase long-term potentiation (L-LTP) in hippocampus, thought to be the cellular basis of long-term memory, requires new protein synthesis. Neural activity enhances local protein synthesis in dendrites, which in turn mediates long-lasting synaptic plasticity. Ca2+/calmodulin-dependent protein ki...

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Bibliographic Details
Main Authors: Itsuko Nihonmatsu, Noriaki Ohkawa, Yoshito Saitoh, Reiko Okubo-Suzuki, Kaoru Inokuchi
Format: Article
Language:English
Published: The Company of Biologists 2020-01-01
Series:Biology Open
Subjects:
camkiiα
camk2a mrna
dentate gyrus
hippocampus
local protein synthesis
long-term potentiation
Online Access:http://bio.biologists.org/content/9/1/bio042861

Internet

http://bio.biologists.org/content/9/1/bio042861

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