Behavioral and pharmacological characteristics of bortezomib-induced peripheral neuropathy in rats

Behavioral and pharmacological characteristics of bortezomib-induced peripheral neuropathy in rats

Bortezomib, an effective anticancer drug for multiple myeloma, often causes peripheral neuropathy which is mainly characterized by numbness and painful paresthesia. Nevertheless, there is no effective strategy to escape or treat bortezomib-induced peripheral neuropathy (BIPN), because we have unders...

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Bibliographic Details
Main Authors: Shota Yamamoto, Takehiro Kawashiri, Hitomi Higuchi, Kuniaki Tsutsumi, Soichiro Ushio, Takanori Kaname, Masafumi Shirahama, Nobuaki Egashira
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Journal of Pharmacological Sciences
Subjects:
Allodynia
Bortezomib-induced neuropathy
Duloxetine
Pregabalin
Tramadol
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861315001814

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http://www.sciencedirect.com/science/article/pii/S1347861315001814

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