Reversible RNA Modification N1-methyladenosine (m1A) in mRNA and tRNA

More than 100 modifications have been found in RNA. Analogous to epigenetic DNA methylation, epitranscriptomic modifications can be written, read, and erased by a complex network of proteins. Apart from N6-methyladenosine (m6A), N1-methyladenosine (m1A) has been found as a reversible modification in...

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Bibliographic Details
Main Authors: Chi Zhang, Guifang Jia
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Genomics, Proteomics & Bioinformatics
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022918301050