The impact of IL18 gene polymorphisms on mRNA levels and interleukin-18 release by peripheral blood mononuclear cells

 The impact of IL18 gene polymorphisms on mRNA levels and interleukin-18 release by peripheral blood mononuclear cells

 Introduction:Interleukin-18 (IL-18) is a pleiotropic cytokine playing an important role as a modulator of immune responses, found to play a role in pathogenesis of numerous inflammatory-associated disorders. In the present study a potential association between 7 common single-nucleotide polymorphis...

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Bibliographic Details
Main Authors: Violetta Dziedziejko, Mateusz Kurzawski, Edyta Paczkowska, Bogusław Machalinski, Andrzej Pawlik
Format: Article
Language:English
Published: Index Copernicus International S.A. 2012-06-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
genetic polymorphism
Interleukin-18
peripheral blood mononuclear cells
stimulants
polimorfizm genetyczny
interleukina 18
jednojądrzaste komórki krwi obwodowej
stymulatory
Online Access:http://journals.indexcopernicus.com/fulltxt.php?ICID=1000980

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