Pediatric Mesenchymal Stem Cells Exhibit Immunomodulatory Properties Toward Allogeneic T and B Cells Under Inflammatory Conditions

Pediatric Mesenchymal Stem Cells Exhibit Immunomodulatory Properties Toward Allogeneic T and B Cells Under Inflammatory Conditions

Mesenchymal stem cells from pediatric patients (pMSCs) are an attractive cell source in regenerative medicine, due to their higher proliferation rates and better differentiation abilities compared to adult MSCs (aMSCs). We have previously characterized the immunomodulatory abilities of pMSCs on T ce...

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Bibliographic Details
Main Authors: Virginia Palomares Cabeza, Martin Johannes Hoogduijn, Rens Kraaijeveld, Marcella Franquesa, Janneke Witte-Bouma, Eppo B. Wolvius, Eric Farrell, Pieter A. J. Brama
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
mesenchymal stem cell
immunomodulation
allogeneic
T cell
B cell
inflammatory microenvironment
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00142/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2019.00142/full

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