Long-Term Caloric Restriction Attenuates β-Amyloid Neuropathology and Is Accompanied by Autophagy in APPswe/PS1delta9 Mice

Caloric restriction (CR) slows the aging process, extends lifespan, and exerts neuroprotective effects. It is widely accepted that CR attenuates β-amyloid (Aβ) neuropathology in models of Alzheimer’s disease (AD) by so-far unknown mechanisms. One promising process induced by CR is autophagy, which i...

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Bibliographic Details
Main Authors: Luisa Müller, Nicole Power Guerra, Jan Stenzel, Claire Rühlmann, Tobias Lindner, Bernd J. Krause, Brigitte Vollmar, Stefan Teipel, Angela Kuhla
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/13/3/985