Isolation and Characterization of Poecistasin, an Anti-Thrombotic Antistasin-Type Serine Protease Inhibitor from Leech <i>Poecilobdella manillensis</i>

Antistasin, first identified as a potent inhibitor of the blood coagulation factor Xa, is a novel family of serine protease inhibitors. In this study, we purified a novel antistasin-type inhibitor from leech <i>Poecilobdella manillensis</i> called poecistasin. Amino acid sequencing of th...

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Bibliographic Details
Main Authors: Xiaopeng Tang, Mengrou Chen, Zilei Duan, James Mwangi, Pengpeng Li, Ren Lai
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/10/11/429