Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma.

BACKGROUND: Osteosarcomas are the most common non-haematological primary malignant tumours of bone, and all conventional osteosarcomas are high-grade tumours showing complex genomic aberrations. We have integrated genome-wide genetic and epigenetic profiles from the EuroBoNeT panel of 19 human osteo...

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Main Authors: Stine H Kresse, Halfdan Rydbeck, Magne Skårn, Heidi M Namløs, Ana H Barragan-Polania, Anne-Marie Cleton-Jansen, Massimo Serra, Knut Liestøl, Pancras C W Hogendoorn, Eivind Hovig, Ola Myklebost, Leonardo A Meza-Zepeda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492335?pdf=render