Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study

Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study

Abstract Background Septic coagulopathy represents a very dynamic disease entity, tilting from initial hypercoagulability towards a subsequent hypocoagulable disease state, entitled overt disseminated intravascular coagulation. Acute fibrinolysis shutdown has recently been described to be a crucial...

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Bibliographic Details
Main Authors: Felix Carl Fabian Schmitt, Vasil Manolov, Jakob Morgenstern, Thomas Fleming, Stefan Heitmeier, Florian Uhle, Mohammed Al-Saeedi, Thilo Hackert, Thomas Bruckner, Herbert Schöchl, Markus Alexander Weigand, Stefan Hofer, Thorsten Brenner
Format: Article
Language:English
Published: SpringerOpen 2019-01-01
Series:Annals of Intensive Care
Subjects:
Fibrinolysis shutdown
Rotational thromboelastometry
Point-of-care testing
Thrombin–antithrombin
Plasminogen activator inhibitor 1
Tissue plasminogen activator
Online Access:http://link.springer.com/article/10.1186/s13613-019-0499-6

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http://link.springer.com/article/10.1186/s13613-019-0499-6

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