Inhibitory effects of Trypanosoma cruzi sialoglycoproteins on CD4+ T cells are associated with increased susceptibility to infection.

Inhibitory effects of Trypanosoma cruzi sialoglycoproteins on CD4+ T cells are associated with increased susceptibility to infection.

<h4>Background</h4>The Trypanosoma cruzi infection is associated with severe T cell unresponsiveness to antigens and mitogens characterized by decreased IL-2 synthesis. Trypanosoma cruzi mucin (Tc Muc) has been implicated in this phenomenom. These molecules contain a unique type of glyco...

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Main Authors: Marise Pinheiro Nunes, Bárbara Fortes, João Luiz Silva-Filho, Eugênia Terra-Granado, Leonardo Santos, Luciana Conde, Isadora de Araújo Oliveira, Leonardo Freire-de-Lima, Marina Vieira Martins, Ana Acacia Sá Pinheiro, Christina Maeda Takyia, Célio Geraldo Freire-de-Lima, Adriane Regina Todeschini, George Alexandre Dosreis, Alexandre Morrot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24204874/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24204874/pdf/?tool=EBI

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