Undercarboxylated osteocalcin correlates with insulin secretion in Japanese individuals with diabetes

Undercarboxylated osteocalcin correlates with insulin secretion in Japanese individuals with diabetes

Abstract Background Undercarboxylated osteocalcin (ucOC) is a secreted protein produced by osteoblasts that regulates insulin secretion and insulin sensitivity in rodents. However, the significance of these effects on glucose metabolism in human remains unknown. Moreover, the pathophysiological role...

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Bibliographic Details
Main Authors: Shogo Funakoshi, Kumiko Yoshimura, Seiki Hirano, Satoko Ohmi, Eri Amano, Yoshiharu Fukuda, Yoshio Terada, Shimpei Fujimoto
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Insulin secretion
BMI
Undercarboxylated osteocalcin
Online Access:http://link.springer.com/article/10.1186/s13098-020-00579-3

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http://link.springer.com/article/10.1186/s13098-020-00579-3

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