Effects of Size and Surface Properties of Nanodiamonds on the Immunogenicity of Plant-Based H5 Protein of A/H5N1 Virus in Mice

Effects of Size and Surface Properties of Nanodiamonds on the Immunogenicity of Plant-Based H5 Protein of A/H5N1 Virus in Mice

Nanodiamond (ND) has recently emerged as a potential nanomaterial for nanovaccine development. Here, a plant-based haemagglutinin protein (H5.c2) of A/H5N1 virus was conjugated with detonation NDs (DND) of 3.7 nm in diameter (ND4), and high-pressure and high-temperature (HPHT) oxidative NDs of ~40–7...

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Bibliographic Details
Main Authors: Thuong Thi Ho, Van Thi Pham, Tra Thi Nguyen, Vy Thai Trinh, Tram Vi, Hsin-Hung Lin, Phuong Minh Thi Nguyen, Huyen Thi Bui, Ngoc Bich Pham, Thao Bich Thi Le, Chi Van Phan, Huan-Cheng Chang, Wesley Wei-Wen Hsiao, Ha Hoang Chu, Minh Dinh Pham
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Nanomaterials
Subjects:
nanodiamond
size effect
surface properties
H5 protein
avian influenza virus A/H5N1
Online Access:https://www.mdpi.com/2079-4991/11/6/1597

Internet

https://www.mdpi.com/2079-4991/11/6/1597

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