Generation and characterization of Men1 mutant mouse models for studying MEN1 disease

Abstract. Patients with multiple endocrine neoplasia type 1 (MEN1) mutations are predisposed to MEN1 syndrome affecting various endocrine cell lineages. Following its identification in the late 1990s, laboratories around the world, including our own, used gene-targeting approaches in murine models t...

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Bibliographic Details
Main Authors: Ya-kun Luo, MS, Razan A. Ziki, MS, Chang X. Zhang, PhD
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2019-06-01
Series:Journal of Pancreatology
Online Access:http://journals.lww.com/10.1097/JP9.0000000000000017