Generation and characterization of Men1 mutant mouse models for studying MEN1 disease
Abstract. Patients with multiple endocrine neoplasia type 1 (MEN1) mutations are predisposed to MEN1 syndrome affecting various endocrine cell lineages. Following its identification in the late 1990s, laboratories around the world, including our own, used gene-targeting approaches in murine models t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Health/LWW
2019-06-01
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Series: | Journal of Pancreatology |
Online Access: | http://journals.lww.com/10.1097/JP9.0000000000000017 |