Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 based vaccines.

The recent 2009 pandemic H1N1 virus infection in humans has resulted in nearly 5,000 deaths worldwide. Early epidemiological findings indicated a low level of infection in the older population (>65 years) with the pandemic virus, and a greater susceptibility in people younger than 35 years of age...

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Bibliographic Details
Main Authors: Balaji Manicassamy, Rafael A Medina, Rong Hai, Tshidi Tsibane, Silke Stertz, Estanislao Nistal-Villán, Peter Palese, Christopher F Basler, Adolfo García-Sastre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20126449/?tool=EBI