Kinetics of CD4+ T Helper and CD8+ Effector T Cell Responses in Acute Dengue Patients

Background: The protective or pathogenic role of T lymphocytes during the acute phase of dengue virus (DENV) infection has not been fully understood despite its importance in immunity and vaccine development.Objectives: This study aimed to clarify the kinetics of T lymphocyte subsets during the clin...

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Main Authors: Dao Huy Manh, Lan Nguyen Weiss, Nguyen Van Thuong, Shusaku Mizukami, Shyam Prakash Dumre, Quang Chan Luong, Le Chi Thanh, Cao Minh Thang, Pham Thanh Huu, Le Hong Phuc, Cao Thi Hong Nhung, Nguyen Thi Mai, Nguyen Quang Truong, Vu Thien Thu Ngu, Do Kien Quoc, Tran Thi Ngoc Ha, Tran Ton, Tran Van An, Oday Halhouli, Le Nhat Quynh, Mohamed Gomaa Kamel, Juntra Karbwang, Vu Thi Que Huong, Nguyen Tien Huy, Kenji Hirayama
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01980/full