Effect of Paclitaxel+Hirudin on the TLR4-MyD88 Signaling Pathway During Inflammatory Activation of Human Coronary Artery Smooth Muscle Cells and Mechanistic Analysis

Effect of Paclitaxel+Hirudin on the TLR4-MyD88 Signaling Pathway During Inflammatory Activation of Human Coronary Artery Smooth Muscle Cells and Mechanistic Analysis

Background/Aims: Approximately 10%-20% of patients with acute cardiovascular disease who have received coronary intervention suffer restenosis and high inflammation. The stent compound paclitaxel+hirudin was prepared for the treatment of post-intervention restenosis. This study aimed to explore the...

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Bibliographic Details
Main Authors: Hongmei Li, Xian Wang, Anlong Xu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Human coronary smooth muscle cells
TLR4/MyD88/NF-κB pathway
Intra-stent restenosis
Thrombosis
Western blot analysis
Online Access:https://www.karger.com/Article/FullText/494588

Internet

https://www.karger.com/Article/FullText/494588

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