Application of Hydration Thermodynamics to the Evaluation of Protein Structures and Protein-Ligand Binding

Discovering the mechanism that controls the three-dimensional structures of proteins, which are closely related to their biological functions, remains a challenge in modern biological science, even for small proteins. From a thermodynamic viewpoint, the native structure of a protein can be understoo...

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Bibliographic Details
Main Author: Yuichi Harano
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Entropy
Subjects:
Online Access:http://www.mdpi.com/1099-4300/14/8/1443