DNA-hydrolysing activity of IgG antibodies from the sera of patients with schizophrenia

DNA-hydrolysing activity of IgG antibodies from the sera of patients with schizophrenia

It is believed that damage to the membranes of brain cells of schizophrenia (SCZ) patients induces the formation of autoantigens and autoantibodies. Nevertheless, the importance of immunological changes leading to the loss of tolerance to self-antigens in the genesis of SCZ has not been established....

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Bibliographic Details
Main Authors: Evgeny A. Ermakov, Ludmila P. Smirnova, Taisiya A. Parkhomenko, Pavel S. Dmitrenok, Nina M. Krotenko, Nikolai S. Fattakhov, Nikolay A. Bokhan, Arkadiy V. Semke, Svetlana A. Ivanova, Valentina N. Buneva, Georgy A. Nevinsky
Format: Article
Language:English
Published: The Royal Society 2015-01-01
Series:Open Biology
Subjects:
schizophrenia
abzymes
dna hydrolysis
autoimmune reactions
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150064

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https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150064

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