Loss of Tet2 affects platelet function but not coagulation in mice

Abstract. Ten-eleven translocation 2 (TET2) functions as a methylcytosine dioxygenase that catalyzes the iterative oxidation of 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine. TET2 has been shown to be crucial for the maintenance and differentiation of hematopoi...

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Bibliographic Details
Main Authors: Bichen Wang, Meijuan Xia, Ting Chen, Mengke Li, Deyang Shi, Xiaomin Wang, Aiming Pang, Jiaxi Zhou, Weiping Yuan, Yajing Chu
Format: Article
Language:English
Published: Wolters Kluwer Health 2020-10-01
Series:Blood Science
Online Access:http://journals.lww.com/10.1097/BS9.0000000000000055