Loss of Tet2 affects platelet function but not coagulation in mice
Abstract. Ten-eleven translocation 2 (TET2) functions as a methylcytosine dioxygenase that catalyzes the iterative oxidation of 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine. TET2 has been shown to be crucial for the maintenance and differentiation of hematopoi...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Health
2020-10-01
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Series: | Blood Science |
Online Access: | http://journals.lww.com/10.1097/BS9.0000000000000055 |