De novo Vessel Formation Through Cross-Talk of Blood-Derived Cells and Mesenchymal Stromal Cells in the Absence of Pre-existing Vascular Structures

De novo Vessel Formation Through Cross-Talk of Blood-Derived Cells and Mesenchymal Stromal Cells in the Absence of Pre-existing Vascular Structures

BackgroundThe generation of functional blood vessels remains a key challenge for regenerative medicine. Optimized in vitro culture set-ups mimicking the in vivo perivascular niche environment during tissue repair may provide information about the biological function and contribution of progenitor ce...

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Bibliographic Details
Main Authors: Beate M. Rüger, Tanja Buchacher, Eva-Maria Dauber, Markus Pasztorek, Pavel Uhrin, Michael B. Fischer, Johannes M. Breuss, Gerda C. Leitner
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
vascular niche model
3D fibrin matrix
mesenchymal stromal cells
endothelial progenitor cells
vasculogenesis
self-organization
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2020.602210/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2020.602210/full

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