Generation of an induced pluripotent stem cell line (GIBHi004-A) from a Parkinson’s disease patient with mutant DJ-1/PARK7 (p.L10P)

Generation of an induced pluripotent stem cell line (GIBHi004-A) from a Parkinson’s disease patient with mutant DJ-1/PARK7 (p.L10P)

Mutations occurring in the gene body of PARK7 (encoding DJ-1/PARK7) cause autosomal recessive early-onset parkinsonism (AREP). These mutations produce a loss of function and have been reported to lead to dopaminergic neuron degeneration in the substantia nigra. However, the underlying mechanisms are...

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Bibliographic Details
Main Authors: Yunpan Li, David P. Ibañez, Wenxia Fan, Ping Zhao, Shuhan Chen, Mazid Md. Abdul, Yu Jiang, Lixin Fu, Zhiwei Luo, Zhenhua Liu, Yueli Yang, Jifeng Guo, Giacomo Volpe, Shahzina Kanwal, Dongye Wang, Beisha Tang, Wenjuan Li
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S187350612030146X

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http://www.sciencedirect.com/science/article/pii/S187350612030146X

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