In Situ<i>-</i>Forming Microparticles for Controlled Release of Rivastigmine: In Vitro Optimization and In Vivo Evaluation

In Situ<i>-</i>Forming Microparticles for Controlled Release of Rivastigmine: In Vitro Optimization and In Vivo Evaluation

In this work, sucrose acetate isobutyrate (SAIB) and polylactic co-glycolic acid (PLGA) were used alone or in combination as a matrix-former (MF) to prepare long-acting injectable rivastigmine (RV) in situ<i>-</i>forming microparticles (ISM). RV-ISM were prepared by the emulsification of...

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Bibliographic Details
Main Authors: Mohamed Haider, Ibrahim Elsayed, Iman S. Ahmed, Ahmed R. Fares
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceuticals
Subjects:
in situ-forming microparticles
rivastigmine
depot release
sucrose acetate isobutyrate
optimization
Online Access:https://www.mdpi.com/1424-8247/14/1/66

Internet

https://www.mdpi.com/1424-8247/14/1/66

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