PRDM16 functions as a suppressor of lung adenocarcinoma metastasis

Abstract Background The transcription factor PR domain containing 16 (PRDM16) is known to play a significant role in the determination and function of brown and beige fat. However, the role of PRDM16 in tumor biology has not been well addressed. Here we investigated the impact of PRDM16 on tumor gro...

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Bibliographic Details
Main Authors: Liang-Ru Fei, Wen-Jing Huang, Yuan Wang, Lei Lei, Zhi-Han Li, Yi-Wen Zheng, Zhao Wang, Mai-Qing Yang, Chen-Chen Liu, Hong-Tao Xu
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
EMT
Online Access:http://link.springer.com/article/10.1186/s13046-019-1042-1