A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples

A facile, green, and high-output hydrothermal synthesis was proposed for the fabrication of highly fluorescent nitrogen-doped carbon quantum dots (N-doped CDs). The nitrogen content in N-doped CDs reached 19.2% and demonstrated strong blue fluorescence emission was obtained with fluorescence quantum...

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Main Authors:	Qianchun Zhang, Siqi Xie, Yanqun Yang, Yun Wu, Xingyi Wang, Jincheng Wu, Li Zhang, Junyu Chen, Yuan Wang
Format:	Article
Language:	English
Published:	Hindawi Limited 2018-01-01
Series:	Journal of Analytical Methods in Chemistry
Online Access:	http://dx.doi.org/10.1155/2018/7890937

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record_format	Article
spelling	doaj-67f263e7902c4b22ab2195b823eb0da12020-11-25T02:16:47ZengHindawi LimitedJournal of Analytical Methods in Chemistry2090-88652090-88732018-01-01201810.1155/2018/78909377890937A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological SamplesQianchun Zhang0Siqi Xie1Yanqun Yang2Yun Wu3Xingyi Wang4Jincheng Wu5Li Zhang6Junyu Chen7Yuan Wang8School of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaA facile, green, and high-output hydrothermal synthesis was proposed for the fabrication of highly fluorescent nitrogen-doped carbon quantum dots (N-doped CDs). The nitrogen content in N-doped CDs reached 19.2% and demonstrated strong blue fluorescence emission was obtained with fluorescence quantum yield (QY) of up to 32.9%, which exhibit high fluorescence quantum yield, high photostability, and excellent biocompatibility. The N-doped CDs possess high photostability, low toxicity, and excellent biocompatibility, based on which the N-doped CDs were successfully applied as a fluorescence probe for cell imaging. Moreover, it was then successfully demonstrated for sensitive and selective detection of Fe3+ in serum.http://dx.doi.org/10.1155/2018/7890937
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Qianchun Zhang Siqi Xie Yanqun Yang Yun Wu Xingyi Wang Jincheng Wu Li Zhang Junyu Chen Yuan Wang
spellingShingle	Qianchun Zhang Siqi Xie Yanqun Yang Yun Wu Xingyi Wang Jincheng Wu Li Zhang Junyu Chen Yuan Wang A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples Journal of Analytical Methods in Chemistry
author_facet	Qianchun Zhang Siqi Xie Yanqun Yang Yun Wu Xingyi Wang Jincheng Wu Li Zhang Junyu Chen Yuan Wang
author_sort	Qianchun Zhang
title	A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples
title_short	A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples
title_full	A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples
title_fullStr	A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples
title_full_unstemmed	A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples
title_sort	facile synthesis of highly nitrogen-doped carbon dots for imaging and detection in biological samples
publisher	Hindawi Limited
series	Journal of Analytical Methods in Chemistry
issn	2090-8865 2090-8873
publishDate	2018-01-01
description	A facile, green, and high-output hydrothermal synthesis was proposed for the fabrication of highly fluorescent nitrogen-doped carbon quantum dots (N-doped CDs). The nitrogen content in N-doped CDs reached 19.2% and demonstrated strong blue fluorescence emission was obtained with fluorescence quantum yield (QY) of up to 32.9%, which exhibit high fluorescence quantum yield, high photostability, and excellent biocompatibility. The N-doped CDs possess high photostability, low toxicity, and excellent biocompatibility, based on which the N-doped CDs were successfully applied as a fluorescence probe for cell imaging. Moreover, it was then successfully demonstrated for sensitive and selective detection of Fe3+ in serum.
url	http://dx.doi.org/10.1155/2018/7890937
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A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples

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