Muscle hypertrophy in transgenic mice due to over-expression of porcine myostatin mutated at its cleavage site

Muscle hypertrophy in transgenic mice due to over-expression of porcine myostatin mutated at its cleavage site

Myostatin, a member of the transforming growth factor beta (TGF-β) superfamily, is a dominant inhibitor that acts to limit skeletal muscle growth and development. In this study, we generated transgenic mice that express porcine myostatin containg mutations at its cleavage site (RSRR) to evaluate its...

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Bibliographic Details
Main Authors: Li-li QIAN, De-zun MA, Peng-fei GAO, Sheng-wang JIANG, Qing-qing WANG, Chun-bo CAI, Gao-jun XIAO, Xiao-rong AN, Wen-tao CUI
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Journal of Integrative Agriculture
Subjects:
porcine myostatin
muscle mass
transgenic mice
mutation
hypertrophy
hyperplasia
Online Access:http://www.sciencedirect.com/science/article/pii/S2095311916613369

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http://www.sciencedirect.com/science/article/pii/S2095311916613369

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