Effect of Gedunin on Acute Articular Inflammation and Hypernociception in Mice

Effect of Gedunin on Acute Articular Inflammation and Hypernociception in Mice

Gedunin, a natural limonoid from Meliaceae species, has been previously described as an antiinflammatory compound in experimental models of allergic inflammation. Here, we report the antiinflammatory and antinociceptive effects of gedunin in an acute model of articular inflammation induced by zymosa...

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Bibliographic Details
Main Authors: Fernando P. Conte, Fausto K. Ferraris, Thadeu E. M. M. Costa, Patricia Pacheco, Leonardo N. Seito, Waldiceu A. Verri Jr., Fernando Q. Cunha, Carmen Penido, Maria G. Henriques
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:Molecules
Subjects:
zymosan
arthritis
edema
neutrophil
macrophage
lipid body
cytokine
leukotriene
prostaglandin
Online Access:http://www.mdpi.com/1420-3049/20/2/2636

Internet

http://www.mdpi.com/1420-3049/20/2/2636

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