Comparative analysis of differential gene expression analysis tools for single-cell RNA sequencing data

Abstract Background The analysis of single-cell RNA sequencing (scRNAseq) data plays an important role in understanding the intrinsic and extrinsic cellular processes in biological and biomedical research. One significant effort in this area is the detection of differentially expressed (DE) genes. s...

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Bibliographic Details
Main Authors: Tianyu Wang, Boyang Li, Craig E. Nelson, Sheida Nabavi
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-019-2599-6