Synthetic Circular RNA Functions as a miR-21 Sponge to Suppress Gastric Carcinoma Cell Proliferation

Synthetic Circular RNA Functions as a miR-21 Sponge to Suppress Gastric Carcinoma Cell Proliferation

MicroRNA (miR) sponges containing miR binding sequences constitute a potentially powerful molecular therapeutic strategy. Recently, naturally occurring circular RNAs (circRNAs) were shown to function as efficient miR sponges in cancer cells. We hypothesized that synthetic circRNA sponges could achie...

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Bibliographic Details
Main Authors: Xi Liu, John M. Abraham, Yulan Cheng, Zhixiong Wang, Zhe Wang, Guanjun Zhang, Hassan Ashktorab, Duane T. Smoot, Robert N. Cole, Tatiana N. Boronina, Lauren R. DeVine, C. Conover Talbot, Jr., Zhengwen Liu, Stephen J. Meltzer
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253118302543

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http://www.sciencedirect.com/science/article/pii/S2162253118302543

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