P27 Protects Neurons from Ischemic Damage by Suppressing Oxidative Stress and Increasing Autophagy in the Hippocampus

P27 Protects Neurons from Ischemic Damage by Suppressing Oxidative Stress and Increasing Autophagy in the Hippocampus

p27<sup>Kip1</sup> (p27), a well-known cell regulator, is involved in the regulation of cell death and survival. In the present study, we observed the effects of p27 against oxidative stress induced by H<sub>2</sub>O<sub>2</sub> in HT22 cells and transient ischemi...

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Bibliographic Details
Main Authors: Woosuk Kim, Hyun Jung Kwon, Hyo Young Jung, Kyu Ri Hahn, Yeo Sung Yoon, In Koo Hwang, Soo Young Choi, Dae Won Kim
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
p27<sup>Kip1</sup>
oxidative stress
ischemia
hippocampus
autophagosome
gerbil
Online Access:https://www.mdpi.com/1422-0067/21/24/9496

Internet

https://www.mdpi.com/1422-0067/21/24/9496

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