Leukocyte-derived hepatic lipase increases HDL and decreases en face aortic atherosclerosis in LDLr−/− mice expressing CETP*s⃞

Leukocyte-derived hepatic lipase increases HDL and decreases en face aortic atherosclerosis in LDLr−/− mice expressing CETP*s⃞

In addition to hepatic expression, cholesteryl ester transfer protein (CETP) and hepatic lipase (HL) are expressed by human macrophages. The combined actions of these proteins have profound effects on HDL structure and function. It is not known how these HDL changes influence atherosclerosis. To elu...

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Bibliographic Details
Main Authors: Neil J. Hime, Audrey S. Black, Josh J. Bulgrien, Linda K. Curtiss
Format: Article
Language:English
Published: Elsevier 2008-10-01
Series:Journal of Lipid Research
Subjects:
cholesteryl ester transfer protein
macrophages
high density lipoproteins
CETPtgLDLr−/− mice
high fat feeding
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520346344

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http://www.sciencedirect.com/science/article/pii/S0022227520346344

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